BAKER BROS. ADVISORS LP 13F Holdings

CIK 0001263508 · New York, NY

As of Sep 30, 2025, BAKER BROS. ADVISORS LP reported 91 positions worth 3.8B in its SEC Form 13F filing.

Top 25 holdings

SecurityTickerSectorSharesValue% of portfolio
BEONE MEDICINES LTDONCHealthcare8,799,053$3.0B21.66%
INCYTE CORPINCYHealthcare30,743,663$2.6B18.84%
MADRIGAL PHARMACEUTICALS INCMDGLHealthcare2,141,701$982.3M7.10%
INSMED INCINSMHealthcare6,703,484$965.4M6.98%
ACADIA PHARMACEUTICALS INCACADHealthcare42,896,690$915.4M6.61%
SUMMIT THERAPEUTICS INCSMMTHealthcare33,722,974$696.7M5.03%
RHYTHM PHARMACEUTICALS INCRYTMHealthcare5,604,483$566.0M4.09%
REVOLUTION MEDICINES INCRVMDHealthcare9,455,357$441.6M3.19%
CELCUITY INCCELC—7,915,792$391.0M2.83%
KYMERA THERAPEUTICS INCKYMRHealthcare6,651,429$376.5M2.72%
KODIAK SCIENCES INCKODHealthcare17,310,490$283.4M2.05%
ALKERMES PLCALKSHealthcare8,091,351$242.7M1.75%
ABCELLERA BIOLOGICS INCABCLHealthcare27,525,640 38.5M1.00%
EDGEWISE THERAPEUTICS INCEWTXHealthcare7,305,940 18.5M0.86%
KINIKSA PHARMACEUTICALS INTERNATIONAL PLCKNSAHealthcare2,824,669 09.7M0.79%
STOKE THERAPEUTICS INCSTOKHealthcare4,633,838 08.9M0.79%
IMMATICS NVIMTXHealthcare12,094,094 03.0M0.74%
GRAIL INCGRALHealthcare1,630,125$96.4M0.70%
IDEAYA BIOSCIENCES INCIDYAHealthcare3,275,444$89.1M0.64%
IMMUNOVANT INCIMVTHealthcare5,457,881$88.0M0.64%
IMMUNOCORE HOLDINGS PLCIMCRHealthcare2,322,656$84.4M0.61%
BICYCLE THERAPEUTICS PLCBCYCHealthcare10,885,357$84.3M0.61%
ULTRAGENYX PHARMACEUTICAL INCRAREHealthcare2,772,692$83.4M0.60%
ABIVAX SAABVXHealthcare875,796$74.4M0.54%
ARROWHEAD PHARMACEUTICALS INCARWRHealthcare1,670,762$57.6M0.42%