EcoR1 Capital, LLC 13F Holdings

CIK 0001587114 · San Francisco, CA

As of Sep 30, 2025, EcoR1 Capital, LLC reported 30 positions worth $2.1B in its SEC Form 13F filing.

Top 25 holdings

SecurityTickerSectorSharesValue% of portfolio
ZYMEWORKS INCZYMEHealthcare22,970,388$392.3M18.83%
ANAPTYSBIO INCANABHealthcare7,880,094$241.3M11.58%
UNIQURE NVQUREHealthcare3,988,971$232.8M11.17%
JAZZ PHARMACEUTICALS PLCJAZZHealthcare1,706,469$224.9M10.79%
CRINETICS PHARMACEUTICALS INCCRNXHealthcare4,288,120 78.6M8.57%
CRISPR THERAPEUTICS AGCRSPHealthcare1,389,276$90.0M4.32%
TANGO THERAPEUTICS INCTNGXHealthcare10,630,736$89.3M4.29%
ORIC PHARMACEUTICALS INCORICHealthcare6,728,116$80.7M3.87%
APELLIS PHARMACEUTICALS INCAPLSHealthcare3,447,156$78.0M3.74%
XENCOR INCXNCRHealthcare6,144,767$72.1M3.46%
GALAPAGOS NVGLPGHealthcare1,667,119$57.7M2.77%
IMMUNOME INCIMNM—4,079,415$47.8M2.29%
ETON PHARMACEUTICALS INCETONHealthcare2,030,544$44.1M2.12%
MBX BIOSCIENCES INCMBXHealthcare2,123,604$37.2M1.78%
MADRIGAL PHARMACEUTICALS INCMDGLHealthcare75,000$34.4M1.65%
AVIDITY BIOSCIENCES INCRNAHealthcare765,000$33.3M1.60%
BRIDGEBIO ONCOLOGY THERAPEUTICS ORDBBOTHealthcare2,823,126$32.7M1.57%
NEUROGENE INCNGNEHealthcare1,271,342$22.0M1.06%
ALKERMES PLCALKSHealthcare500,000 5.0M0.72%
AQUESTIVE THERAPEUTICS INCAQSTHealthcare2,625,000 4.7M0.70%
METSERA INCMTSRHealthcare271,529 4.2M0.68%
CENTESSA PHARMACEUTICALS PLCCNTAHealthcare550,000 3.3M0.64%
PRIME MEDICINE INCPRMEHealthcare1,543,326$8.6M0.41%
ATARA BIOTHERAPEUTICS INCATRAHealthcare573,183$8.2M0.39%
KURA ONCOLOGY INCKURAHealthcare872,500$7.7M0.37%