HighVista Strategies LLC 13F Holdings

CIK 0001335325 · BOSTON, MA

As of Sep 30, 2025, HighVista Strategies LLC reported 148 positions worth $408.0M in its SEC Form 13F filing.

Top 25 holdings

SecurityTickerSectorSharesValue% of portfolio
INVESCO DB COMMODITY INDEX TRACKING FUNDDBC—1,436,136$32.4M7.93%
ABIVAX SAABVXHealthcare184,468 5.7M3.84%
MERUS NVMRUSHealthcare133,321 2.6M3.08%
VIRIDIAN THERAPEUTICS INCVRDNHealthcare469,335 0.1M2.48%
REVOLUTION MEDICINES INCRVMDHealthcare175,448$8.2M2.01%
PROTAGONIST THERAPEUTICS INCPTGXHealthcare121,682$8.1M1.98%
NUVALENT INCNUVLHealthcare93,294$8.1M1.98%
MINERALYS THERAPEUTICS INCMLYSHealthcare209,829$8.0M1.95%
ARCELLX INCACLXHealthcare96,177$7.9M1.94%
AGIOS PHARMACEUTICALS INCAGIOHealthcare195,298$7.8M1.92%
CYTOKINETICS INCCYTKHealthcare132,930$7.3M1.79%
INSMED INCINSMHealthcare49,949$7.2M1.76%
CIDARA THERAPEUTICS INCCDTXHealthcare70,904$6.8M1.66%
COGENT BIOSCIENCES INCCOGTHealthcare462,405$6.6M1.63%
STRUCTURE THERAPEUTICS INCGPCRHealthcare236,236$6.6M1.62%
AMAZON.COM INCAMZNEquity26,393$5.8M1.42%
SANDISK CORPSNDKTechnology47,451$5.3M1.31%
ENLIVEN THERAPEUTICS INCELVNHealthcare259,135$5.3M1.30%
AKERO THERAPEUTICS INCAKROHealthcare110,079$5.2M1.28%
PRAXIS PRECISION MEDICINES INCPRAXHealthcare95,002$5.0M1.23%
MICROSOFT CORPMSFTTechnology9,458$4.9M1.20%
OLEMA PHARMACEUTICALS INCOLMAHealthcare437,179$4.3M1.05%
BRIDGEBIO PHARMA INCBBIOHealthcare81,959$4.3M1.04%
APOGEE THERAPEUTICS INCAPGEHealthcare107,107$4.3M1.04%
IMMUNOVANT INCIMVTHealthcare253,127$4.1M1.00%