ORBIMED ADVISORS LLC 13F Holdings

CIK 0001055951 · New York, NY

As of Sep 30, 2025, ORBIMED ADVISORS LLC reported 104 positions worth $4.3B in its SEC Form 13F filing.

Top 25 holdings

SecurityTickerSectorSharesValue% of portfolio
BOSTON SCIENTIFIC CORPBSXHealthcare2,629,300$256.7M6.03%
EDGEWISE THERAPEUTICS INCEWTXHealthcare15,518,492$251.7M5.92%
ELI LILLY & COLLYHealthcare301,200$229.8M5.40%
SINOVAC BIOTECH LTDSVAHealthcare2,718,735 84.5M4.33%
ENLIVEN THERAPEUTICS INCELVNHealthcare7,959,538 62.9M3.83%
ALNYLAM PHARMACEUTICALS INCALNYHealthcare301,600 37.5M3.23%
STRYKER CORPSYKHealthcare359,200 32.8M3.12%
EDWARDS LIFESCIENCES CORPEWHealthcare1,684,000 31.0M3.08%
INTUITIVE SURGICAL INCISRGHealthcare287,200 28.4M3.02%
ARGENX SEARGXHealthcare172,300 27.1M2.99%
SIONNA THERAPEUTICS INCSIONHealthcare3,704,959 09.0M2.56%
UPSTREAM BIO INCUPBHealthcare5,693,589 07.1M2.52%
DISC MEDICINE INCIRONHealthcare1,415,020$93.5M2.20%
CARIS LIFE SCIENCES INCCAIHealthcare3,034,858$91.8M2.16%
ARS PHARMACEUTICALS INCSPRYHealthcare8,288,510$83.3M1.96%
AVIDITY BIOSCIENCES INCRNAHealthcare1,638,886$71.4M1.68%
MBX BIOSCIENCES INCMBXHealthcare4,002,887$70.1M1.65%
CG ONCOLOGY INCCGONHealthcare1,726,850$69.6M1.63%
NATERA INCNTRAHealthcare429,300$69.1M1.62%
AXSOME THERAPEUTICS INCAXSMHealthcare531,800$64.6M1.52%
APELLIS PHARMACEUTICALS INCAPLSHealthcare2,573,368$58.2M1.37%
TERNS PHARMACEUTICALS INCTERNHealthcare7,562,971$56.8M1.33%
ARRIVENT BIOPHARMA INCAVBPHealthcare3,027,328$55.9M1.31%
MINERALYS THERAPEUTICS INCMLYSHealthcare1,469,494$55.7M1.31%
EXACT SCIENCES CORPEXASHealthcare994,616$54.4M1.28%