Paradigm Biocapital Advisors LP 13F Holdings

CIK 0001855655 · NEW YORK, NY

As of Sep 30, 2025, Paradigm Biocapital Advisors LP reported 34 positions worth $3.5B in its SEC Form 13F filing.

Top 25 holdings

SecurityTickerSectorSharesValue% of portfolio
NUVALENT INCNUVLHealthcare5,269,433$455.7M12.96%
MERUS NVMRUSHealthcare4,673,770$440.0M12.51%
ARCELLX INCACLXHealthcare4,649,016$381.7M10.86%
REVOLUTION MEDICINES INCRVMDHealthcare6,223,291$290.6M8.27%
TARSUS PHARMACEUTICALS INCTARSHealthcare2,665,698 58.4M4.51%
VAXCYTE INCPCVXHealthcare3,784,755 36.3M3.88%
ABIVAX SAABVXHealthcare1,564,196 32.8M3.78%
GENMAB AGMABHealthcare3,816,851 17.1M3.33%
AGIOS PHARMACEUTICALS INCAGIOHealthcare2,873,555 15.3M3.28%
CRINETICS PHARMACEUTICALS INCCRNXHealthcare2,550,774 06.2M3.02%
STATE STREET(R) SPDR(R) S&P(R) BIOTECH ETFXBI—1,000,000 00.2M2.85%
EDGEWISE THERAPEUTICS INCEWTXHealthcare6,170,131 00.1M2.85%
CIDARA THERAPEUTICS INCCDTXHealthcare961,164$92.0M2.62%
UROGEN PHARMA LTDURGNHealthcare4,216,084$84.1M2.39%
SCHOLAR ROCK HOLDING CORPSRRKHealthcare2,009,745$74.8M2.13%
JANUX THERAPEUTICS INCJANXHealthcare2,920,258$71.4M2.03%
OLEMA PHARMACEUTICALS INCOLMAHealthcare6,794,172$66.5M1.89%
APOGEE THERAPEUTICS INCAPGEHealthcare1,521,757$60.5M1.72%
VIRIDIAN THERAPEUTICS INCVRDNHealthcare2,609,353$56.3M1.60%
ALKERMES PLCALKSHealthcare1,719,334$51.6M1.47%
LENZ THERAPEUTICS INCLENZHealthcare1,073,461$50.0M1.42%
PHARVARIS N VPHVSHealthcare1,835,494$45.8M1.30%
COGENT BIOSCIENCES INCCOGTHealthcare3,156,398$45.3M1.29%
OCULAR THERAPEUTIX INCOCULHealthcare3,497,307$40.9M1.16%
BRIDGEBIO PHARMA INCBBIOHealthcare684,277$35.5M1.01%